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CJC-1295 is a synthetic, modified version of the first 29 amino acids of growth hormone-releasing hormone (GHRH), with DAC referring to the added chemical compound that prolongs the plasma half-life of CJC-1295. The peptide binds to receptors in the pituitary gland to promote the release of growth hormone (GH) and insulin-like growth factor 1 (IGF-1).


Higher levels of both GH and IGF-1 have been linked to increased lean muscle mass and reduced fat, hence why CJC-1295 has been investigated to treat lipodystrophy and growth hormone deficiency. Researchers are also studying CJC-1295 for its potential anti-aging and sleep promoting effects.

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    What Is CJC-1295?

    CJC-1295 is a peptide, often known by other names like CJC-1295 DAC, or DAC:GRF (which stands for drug affinity complex: growth hormone-releasing factor). It’s a synthetic peptide that helps regulate growth hormone levels [1].

    So what does it do?

    CJC-1295 is a chemical analog to one of the body’s natural hormones called growth hormone-releasing hormone (GHRH) [2]. Because the two have a similar chemical structure, CJC-1295 does the same thing as GHRH: It stimulates the body to produce and release more growth hormone (GH) [3].

    That means it increases the amount of GH that makes it into the bloodstream and to the cells. GH is essential for stimulating cell growth, cell reproduction, and regeneration [4]. Since growth hormone is used in so many bodily processes, CJC-1295 purportedly makes those processes more efficient.

    CJC-1295 is just one of several GHRH analogs like Sermorelin and Tesamorelin.

    One of the differences between CJC-1295 and other GH secretagogues is that CJC preserves the normal physiological release of GH. That means that while it does increase GH in the bloodstream, it follows the normal circadian rhythm of peaks and valleys in concentration, which helps reduce side effects [5].

    It also lasts longer. While natural growth hormone-releasing hormone has a half-life of about seven minutes [6], CJC-1295 DAC has a half-life of 6 to 8 days in humans and so its effects can persist for weeks [3]. In other words, it’s powerful.

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    Benefits of CJC-1295

    The CJC-1295 peptide’s primary benefit is that it upregulates the body’s natural growth hormone. That, in turn, may entail several benefits for research subjects.

    The purported benefits of CJC-1295 include:

    • Increased bone density: Bones tend to get brittle and lose density as we age. increased GH may help restore that bone density [7].
    • Increased muscle mass: GH makes it easier to build muscle after exercise and prepares the body to repair muscle tissue [8, 9]. That’s one reason why CJC-1295 band body composition has become a popular research subject.
    • Better sleep: CJC-1295 may improve the quality of sleep (and the frequency of vivid dreams) [10].
    • The ability to burn fat: GH has helped research subjects get the most out of workouts and burn through stubborn body fat [8]. It’s not magic, but with exercise, they usually see results [11].
    • Better recovery from injuries: GH increases the body's ability to repair itself when tissue is damaged [12].
    • Smoother, younger-looking skin: GH helps improve the quality of the skin because it helps repair the collagen that is responsible for skin elasticity and fullness [13, 14].

    Considering all these potential benefits of CJC-1295, the research applications and study potential is endless.

    CJC-1295 Side Effects

    The few scientific studies involving CJC-1295 that have been conducted to date have found that it causes no serious adverse reactions among test subjects [3, 5]. Peptides in general tend to have few side effects because they are so close to the body’s own signals — they aren’t adding a new chemical compound to the body.

    Still, it’s possible that some research subjects could experience side effects. These may include [5]:

    • redness and tenderness at injection site
    • increased heart rate
    • headache
    • nausea
    • dizziness
    • flushing
    • hives
    • hyperactivity
    • difficulty swallowing
    • flu-like symptoms

    Side effects of CJC-1295 appear to be dose-dependent, which means that they become more likely the higher the dose that one is administered. Since a normal dose appears to be twice a week at 100 mcg, taking more than that puts test subjects at a greater risk of experiencing side effects.

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    Where to Buy CJC-1295 Online? | 2024 Edition

    Researchers intent on purchasing CJC-1295 online from an online source are well-advised to consider important factors like:

    • Peptide production processes
    • Third-party lab testing
    • Shipping policies
    • Support and service
    • Industry reputation

    Based on these criteria, we highly recommend the following vendors of research-grade reference materials:

    CJC-1295 No DAC

    For researchers looking to source CJC-1295 No DAC, we can safely recommend:

    Limitless Life

    Limitless Life is our preferred research peptide vendor at

    We like Limitless Life because of their outstanding quality control measures, their extremely responsive service team, their BBB-accreditation, and their quick domestic and international shipping options.

    Here’s a little bit more information about why we prefer Limitless Life to other vendors:

    • Independent Quality Testing: Limitless Life offers products with a purity rating of 99% or greater. This is validated through independent laboratory testing.
    •  Service Availability: Limitless Life’s service team is available 7 days per week. This helps ensure that questions and order concerns are addressed quickly.
    • BBB-Accreditation: Limitless Life has been recognized by both the Better Business Bureau and Dun and Bradstreet for their superior business practices.
    • Fast Domestic and International Shipping: Limitless Life strives to have all orders shipped out within 48 hours of the order being placed. They use reliable domestic shipping via FedEx and offer fast international options as well.

    Additionally, peptide researchers are eligible for a 10% discount on their next Limitless Life order using our exclusive discount code. Click the banner below and then add this code at checkout:


    Buy CJC-1295 No DAC from our top-rated vendor...

    CJC-1295 DAC

    For researchers interested in CJC-1295 DAC, we recommend this top-rated peptides company:

    Research Chemical

    Here's what this vendor does well:

    • Purity Testing: Research Chemical makes sure all their CJC-1295 DAC is purity tested with professional third-party labs. Once they confirm the purity and quality of the peptide batch, they show the results on their website.
    • Quick, Simple Shipping: With same-day and next-day fulfillment standard, Research Chemical gets peptides shipped quickly. Shipping costs are also quite low here.
    • Various Payment Options: Research Chemical offers a few different payment options. They accept all major credit cards, along with crypto payments.

    Buy CJC-1295 from our top-rated vendor...

    CJC-1295 No DAC + Ipamorelin

    When looking for a CJC-1295 No DAC + Ipamorelin blend, we recommend researchers look here again:

    Limitless Life

    Bacteriostatic Water and CJC-1295

    In addition to quality CJC-1295 from a reputable source, researchers should have the required supplementary materials on hand for proper handling.

    When it comes to safe and effective methods of peptide preparation, storage, and application, items such as sterile vials, alcohol swabs, and bacteriostatic water are indispensable.

    CJC-1295 For Sale | Verdict

    CJC-1295 is a powerful peptide that may be of interest to peptide researchers. Test subjects have experienced dramatic changes in their body composition (more muscle, less fat), general appearance, and well-being from this peptide.

    There are some possible side effects, but to date, these have typically been rare and minor. Following correct dosing guidelines will help research subjects avoid these.

    The only real issue is where to buy CJC-1295. To help resolve this issue, our team has tested multiple peptide vendors and identified a clear winner:  Limitless Life

    Here are a few reasons why we rate them so highly:

    • Real, high-quality peptides
    • Fast, accurate shipping with no delays
    • Reasonable prices on all products
    • Friendly, responsive service

    Researchers interested in working with CJC-1295 are advised to check out their website for more information.


    1. Jetté, L., Léger, R., Thibaudeau, K., Benquet, C., Robitaille, M., Pellerin, I., ... & Bridon, D. P. (2005). hGRF1-29-Albumin Bioconjugates Activate the GRF Receptor on the Anterior Pituitary in Rats: Identification of CJC-1295 as a Long Lasting GRF Analog. Endocrinology, 146(7), 3052–3058.
    2. Alba, M., Fintini, D., Sagazio, A., Lawrence, B., Castaigne, J. P., Frohman, L. A., & Salvatori, R. (2006). Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. American Journal of Physiology-Endocrinology and Metabolism, 291(6), E1290-E1294.
    3. Teichman, S. L., Neale, A., Lawrence, B., Gagnon, C., Castaigne, J. P., & Frohman, L. A. (2006). Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. The Journal of Clinical Endocrinology & Metabolism, 91(3), 799-805.
    4. Florini, J. R. (1987). Hormonal control of muscle growth. Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine, 10(7), 577-598.
    5. Ionescu, M., & Frohman, L. A. (2006). Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. The Journal of Clinical Endocrinology & Metabolism, 91(12), 4792-4797.
    6. Van Hout, M. C., & Hearne, E. (2016). Netnography of female use of the synthetic growth hormone CJC-1295: pulses and potions. Substance Use & Misuse, 51(1), 73-84.
    7. Landin‐Wilhelmsen, K., Nilsson, A., Bosaeus, I., & Bengtsson, B. Å. (2003). Growth hormone increases bone mineral content in postmenopausal osteoporosis: a randomized placebo‐controlled trial. Journal of Bone and Mineral Research, 18(3), 393-405.
    8. Thompson, J. L., Butterfield, G. E., Gylfadottir, U. K., Yesavage, J., Marcus, R., Hintz, R. L., ... & Hoffman, A. R. (1998). Effects of human growth hormone, insulin-like growth factor I, and diet and exercise on body composition of obese postmenopausal women. The Journal of Clinical Endocrinology & Metabolism, 83(5), 1477-1484.
    9. Welle, S., Thornton, C., Statt, M., & McHenry, B. (1996). Growth hormone increases muscle mass and strength but does not rejuvenate myofibrillar protein synthesis in healthy subjects over 60 years old. The Journal of Clinical Endocrinology & Metabolism, 81(9), 3239-3243.
    10. Ghigo, E., Arvat, E., Giordano, R., Broglio, F., Gianotti, L., Maccario, M., ... & Camanni, F. (2001). Biologic activities of growth hormone secretagogues in humans. Endocrine, 14(1), 87-93.
    11. Taaffe, D. R., Pruitt, L., Reim, J., Hintz, R. L., Butterfield, G., Hoffman, A. R., & Marcus, R. (1994). Effect of recombinant human growth hormone on the muscle strength response to resistance exercise in elderly men. The Journal of Clinical Endocrinology & Metabolism, 79(5), 1361-1366.
    12. Erotokritou-Mulligan, I., Holt, R. I., & Sönksen, P. H. (2011). Growth hormone doping: a review. Open Access Journal of Sports Medicine, 2, 99.
    13. Ganceviciene, R., Liakou, A. I., Theodoridis, A., Makrantonaki, E., & Zouboulis, C. C. (2012). Skin anti-aging strategies. Dermato-endocrinology, 4(3), 308-319.
    14. Bartke, A. (2019). Growth hormone and aging: updated review. The World Journal of Men's Health, 37(1), 19-24.


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