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Tesamorelin is a synthetic analogue of human growth hormone-releasing hormone (GHRH). Used to stimulate the manufacture and release of growth hormone, tesamorelin’s 44 amino acid chain is based on GHRH’s, plus a trans-3-hexenoic acid group that makes it more stable and longer-lasting than natural GHRH.


Highly effective at increasing growth hormone synthesis and release in the body, tesamorelin is an FDA-approved treatment of lipodystrophy in HIV-afflicted individuals. Researchers are now investigating tesamorelin in a variety of fat reduction and body composition improvement contexts.

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    What is Tesamorelin?

    Let's start with the basics: What is tesamorelin?

    Tesamorelin is a synthetic peptide that belongs to a class of medications known as growth hormone-releasing hormones (GHRHs) [1, 2, 3].

    Because it’s virtually identical to endogenous GHRH in chemical structure, tesamorelin has essentially the same effect as GHRH. It acts as a growth hormone-releasing factor analogue that stimulates the release of human growth hormone (HGH). In 2010, Tesamorelin was approved by the US FDA for the treatment of lipodystrophy in HIV patients, Lipodystrophy refers to a syndrome that involves changes in fat distribution and metabolism, often seen in individuals receiving antiretroviral therapy (ART) for the management of HIV infection.

    Why is HGH a big deal?

    HGH is essential for humans — it's involved in practically all of the processes related to creating and repairing new tissue [4]. It stimulates cell growth and reproduction.

    That means that it's involved in how children develop into adults and affect their growth. But more fundamentally, it's what's at work when your muscles are repairing themselves after a workout, when your skin is regenerating old cells, and when your body is producing immune cells.

    HGH has been implicated in a great number of essential processes:

    • Increasing muscle mass
    • Promoting lipolysis (the metabolism of fat into energy)
    • Increasing protein synthesis
    • Stimulating organ growth
    • Helping keep body temperature balanced

    HGH levels drop with age

    As we age, the concentration of HGH in our blood declines. That's part of the reason our body is slower to recover and regenerate as we get older.

    Tesamorelin increases HGH concentrations

    Tesamorelin is one of a family of GHRHs, including pralmorelin [5] and EP1572 [6], that work by stimulating the subject’s body to produce and secrete more HGH, leading to higher levels of concentration. Increased HGH means increased ability for the subject’s body to grow, regenerate and stay healthy.


    Where to Buy Tesamorelin Online?

    In the United States as well as most other countries, it's legal to order tesamorelin online for research purposes. And it's easy to do.

    But unfortunately, not every vendor is legitimate. Some of them pack their peptides with fillers or other bad stuff. This can be not only disappointing but can also be harmful to your research subjects.

    Finding a legitimate vendor

    So how can you find a legitimate vendor? Here are athe few of the factors that you can look for.

    1. Look for disclaimers. Legitimate sites will have very clear disclaimers about what the product is for — and what it isn't for. Disclaimers are a good sign because they signal that the company takes its responsibility before the law seriously.
    2. Look for science. On this site, we undertake extensive research to make sure we're providing our readers with accurate, up-to-date information. Legitimate vendors will do this, too. Lots of references to high-quality research are a good sign.
    3. Look for test results. You want to make sure that your vendor is selling a pure product. Legitimate vendors will publish laboratory results proving that their products are up to high research standards and are pure.
    4. Return and refund policy. Mistakes with orders happen — even with legitimate companies. But you want to know that your vendor will fix any mistakes that occur. Look to see if they offer a money-back guarantee or will commit to re-shipping if the order was defective in some way.
    5. The other stuff. Also consider that your ideal vendor will have good customer service, a good reputation in the community, and good reviews from independent third-party sites. It's also great if they accept a variety of payment options and will ship to your country at a reasonable price.

    Buy Tesamorelin from our #1 recommended vendor...

    The #1 Place to Legally Buy Tesamorelin

    In our experience, the best place to buy tesamorelin online is Peptide Sciences. There are several reasons as to why we hold them in such high regard. Most importantly, they ship high-quality products.

    Peptide Science offers the highest quality peptides that we have tested. They post certificates of analysis for all peptides online so researchers can verify the quality before placing an order. As the researcher, you get peace of mind in knowing exactly what you're paying for when you buy from this vendor.

    What else? Peptide Sciences also offers:

    • Secure shopping: Peptide Sciences use SSL technology to make sure that personal information is not stolen or compromised.
    • International shipping: Researchers can place orders from almost anywhere worldwide and be assured that their shipment will arrive.
    • Reasonable prices: Peptide Sciences always has fair prices for the high-quality products that they provide.
    • Great customer service: Researchers can get in touch with Peptide Sciences at any time and speak with a real person.

    Researchers interested in buying tesamorelin online are highly advised to contact Peptide Sciences. This vendor ships 100% authentic peptides and has a stellar track record.

    How to Order Tesamorelin | Country-By-Country

    To find out if you can order tesamorelin in your country, simply go to the Peptide Sciences website and fill out an order. Choose your product, add it to the cart, and go to the checkout page.

    In the billing information box, you'll see that you have to fill out your billing address, including the country. Open the country dialog box to see if your country is one of the options.

    If it is, you're good to go.

    You'll see that they will ship to many, many countries, including throughout the US, the UK, and Canada.

    buy ipamorelin

    Tesamorelin vs. Ipamorelin?

    If you’re curious about the key differences between tesamorelin and ipamorelin, this is the section for you. Both of these substances are peptides that stimulate the release of growth hormone (GH). However, there are a couple of key differences that researchers should be aware of before designing their research project.

    First, only tesamorelin has been approved by the FDA for human use. Its approved use is to treat HIV-infected patients who suffer from excess abdominal body fat [7]. To date, ipamorelin has not been FDA-approved for this or any other purpose and remains a research peptide.

    The second key difference between tesamorelin and ipamorelin is that ipamorelin’s purported benefits come from laboratory animal studies, not human clinical trials. Ipamorelin is a selective growth hormone secretagogue that has been tested on swine and found to increase GHRH stimulation without affecting cortisol plasma or adrenocorticotropic hormone (ACTH) levels [8]. It has also been tested on rats and shown to stimulate body weight gain and GH release [9].

    While both of these peptides can stimulate GH levels, these are the two main differences that researchers should bear in mind.

    Tesamorelin For Sale | FAQ

    Still have a question? Here are some frequently asked questions about buying tesamorelin online.

    Who makes tesamorelin?

    Tesamorelin was originally developed by a Canadian company called Theratechnologies, Inc. [2], but several firms around the world now market tesamorelin for sale. One of the major American producers of tesamorelin is Peptide Sciences.

    How much does tesamorelin cost?

    You'll find tesamorelin for sale at a range of prices. In our experience, you can buy 2 mg for approximately $35 and 5 mg for about $70. Peptide Sciences also sells a 10-pack of 2 mg vials for $285.

    A typical dose of tesamorelin is 1 mg to 2 mg per day. At the low dosage, a 5 mg vial would last a week on a research cycle of 5 days on, 2 days off. At this protocol, the cost would be $70 per week.

    Some vendors also offer discounts for bulk shipping.

    Do you need a prescription to buy tesamorelin online?

    No, provided you’re not using the compound as a drug — in which case it is only approved for the treatment of HIV-associated lipodystrophy.

    Tesamorelin is available for sale — without a prescription — for research purposes only. Do not handle this compound unless you’re a qualified professional.


    Benefits of Tesamorelin

    So what are the benefits of tesamorelin — how might your research subjects benefit from it in the first place?

    While tesamorelin has been around for a while, scientists are still coming to understand how it can be used. There has been a lot of research conducted on its particular effects. For example, there has been extensive research on its effects on people taking HIV medications.

    But in other areas, research on its full benefits is lacking.

    Still, the literature does provide insight into the potential effects of tesamorelin:

    • Muscle growth: We know that HGH leads to muscle growth, and there's some indication that tesamorelin does, too. Studies on HIV patients have found that tesamorelin significantly increases muscle density and size in those patients [10].
    • Fat loss: The results of two randomized, placebo-controlled trials showed that tesamorelin w can reduce the amount of visceral adipose tissue (VAT) in HIV-infected patients that had received antiretroviral therapy [7].
    • Decrease risk of cardiovascular disease: One study found that tesamorelin could “significantly decrease” fat in the abdominal subcutaneous tissues and may decrease cardiovascular risk in HIV patients [11].
    • Nerve Damage. Nerve cells don't regenerate easily, but some research suggests that Growth Hormone (GH)-based therapies, such as tesamorelin, may be able to improve nerve regeneration [12].
    • Cognitive enhancement. Research suggests there is some promise for tesamorelin in reducing cognitive decline, improving outcomes for individuals with early stages of dementia, and enhancing cognition among healthy individuals [13].

    Tesamorelin Side Effects

    Tesamorelin has been well-tolerated by most individuals. One 12-week study about the safety of tesamorelin for patients with type 2 diabetes found that it had no effect on glycemic control and “did not alter insulin response” [14].

    Another study about the long-term safety and adverse effects of tesamorelin in HIV-infected patients found that tesamorelin decreased triglycerides and visceral adipose tissue (VAT) over 52 weeks “without aggravating glucose” [15].

    But, as with almost any substance, there are side effects of which all researchers should be aware. Studies performed on HIV-positive patients indicated that common tesamorelin side effects include [11]:

    • redness, itching, pain, swelling, and irritation at the site of injection
    • muscle aches
    • Diarrhea
    • Sweating

    More serious side effects can occur as well, but these are less common. They include:

    • Neuropathies
    • diarrhea with fever and dehydration
    • congestive heart failure
    • shortness of breath

    • muscle or joint pain numbness, tingling, swelling in arms or legs

    Bacteriostatic Water For Injection

    When experimenting with peptides like Tesamorelin, researchers can’t neglect the importance of a properly equipped lab.

    To adhere to the proper measures of peptide administration, prep, and storage, your toolkit should include insulin syringes, bac water, and sterile vials, to list just a few of the necessities.

    While some researchers struggle to equip their labs, spending hours searching the web and navigating low-quality vendors, you don’t have to! is pleased to reveal your top resource for all lab requirements when handling research peptides.

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    Tesamorelin For Sale | Verdict

    Researchers interested in where to buy tesamorelin online will note that while this peptide’s clinical use in the United States is limited to the treatment of HIV patients with lipodystrophy, it is effective at increasing HGH in the body and, in theory, this may help test subjects build muscle, burn fat, and regenerate tissue. It may even help with cognitive enhancement.

    While it is available by prescription for certain applications, researchers can obtain tesamorelin from online vendors of research peptides like Peptide Sciences. This vendor is convenient, easy to use, and ships to pretty much anywhere in the world.

    Happy Researching!


    1. Food and Drug Administration (2010). Chemistry Reviews: Application 22-505.
    2. Patel, A., Gandhi, H., & Upaganlawar, A. (2011). Tesamorelin: A hope for ART-induced lipodystrophy. Journal of Pharmacy And Bioallied Sciences, 3(2), 319.
    3. Dhillon, S. (2011). Tesamorelin. Drugs, 71(8), 1071-1091.
    4. Florini, J. R. (1987). Hormonal control of muscle growth. Muscle & Nerve: Official Journal of the American Association of Electrodiagnostic Medicine, 10(7), 577-598.
    5. Editorial, A. (2004). Pralmorelin: GHRP 2, GPA 748, Growth Hormone-Releasing Peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN. Drugs in R & D, 5, 236-239.
    6. Broglio, F., Boutignon, F., Benso, A., Gottero, C., Prodam, F., Arvat, E., ... & Muccioli, G. (2002). EP1572: a novel peptidomimetic GH secretagogue with potent and selective GH-releasing activity in man. Journal of Endocrinological Investigation, 25(8), RC26-RC28.
    7. Falutz J, Mamputu JC, Potvin D, Moyle G, Soulban G, Loughrey H, Marsolais C, Turner R, Grinspoon S. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data. J Clin Endocrinol Metab. 2010 Sep;95(9):4291-304. doi: 10.1210/jc.2010-0490. Epub 2010 Jun 16. PMID: 20554713.
    8. Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61. doi: 10.1530/eje.0.1390552. PMID: 9849822.
    9. Jiménez-Reina, L., Cañete, R., De la Torre, M. J., & Bernal, G. (2002). Chronic in vivo Ipamorelin treatment stimulates body weight gain and growth hormone (GH) release in vitro in young female rats. European Journal of Anatomy, 6(1), 37-45.
    10. Adrian, S., Scherzinger, A., Sanyal, A., Lake, J. E., Falutz, J., Dubé, M. P., ... & Brown, T. T. (2019). The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV. The Journal of Frailty & Aging, 8(3), 154-159.
    11. Falutz, J., Allas, S., Blot, K., Potvin, D., Kotler, D., Somero, M., ... & Turner, R. (2007). Metabolic effects of a growth hormone–releasing factor in patients with HIV. New England Journal of Medicine, 357(23), 2359-2370.
    12. Tuffaha, S. H., Singh, P., Budihardjo, J. D., Means, K. R., Higgins, J. P., Shores, J. T., ... & Brandacher, G. (2016). Therapeutic augmentation of the growth hormone axis to improve outcomes following peripheral nerve injury. Expert Opinion on Therapeutic Targets, 20(10), 1259-1265.
    13. Friedman, S. D., Baker, L. D., Borson, S., Jensen, J. E., Barsness, S. M., Craft, S., ... & Vitiello, M. V. (2013). Growth Hormone–Releasing Hormone Effects on Brain γ-Aminobutyric Acid Levels in Mild Cognitive Impairment and Healthy Aging. JAMA Neurology, 70(7), 883-890.
    14. Clemmons DR, Miller S, Mamputu JC. Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial. PLoS One. 2017 Jun 15;12(6):e0179538. doi: 10.1371/journal.pone.0179538. PMID: 28617838; PMCID: PMC5472315.
    15. Falutz J, Allas S, Mamputu JC, Potvin D, Kotler D, Somero M, Berger D, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S. Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation. AIDS. 2008 Sep 12;22(14):1719-28. doi: 10.1097/QAD.0b013e32830a5058. PMID: 18690162.


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