Tesamorelin Benefits | The #1 A-Z Guide

Curious about tesamorelin benefits?

Then keep reading, as we detail in this guide what researchers can expect when they experiment with this reference material. 

Tesamorelin is one of several human growth hormone (HGH) secretagogues, substances that increase HGH and improve the body's ability to create and repair tissues. When administered to individuals with lipodystrophy, tesamorelin is especially effective at burning through stubborn abdominal fat.

But what else can it do?

Find out here. In this A-Z guide, researchers will find a concise overview of the benefits offered by tesamorelin based on high-quality scientific research. Below, researchers will gain a full understanding of how tesamorelin works, the side effects it causes, and what researchers can expect when they run an experiment or trial with this peptide. 

Let’s get started!

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What is Tesamorelin?

Tesamorelin is a peptide. Peptides are long sequences of amino acids that play an important role in the body's chemical signaling processes. They help keep cells healthy [1].

We know that peptides play an important role in human health, and there are about 60 of them that are currently of interest to scientists looking to solve the hardest problems in health. Tesamorelin is one of the peptides that looks like it could play an especially important role in tissue growth and repair.

Tesamorelin is made up of a sequence of 44 amino acids. It is virtually identical to a hormone that the  body produces naturally called growth hormone-releasing hormone (GHRH) [2].

GHRH is deeply important to how the body regulates the HGH levels in your blood.

HGH is essential to human growth and performance. It is a critical part of the process by which the body builds and repairs tissue. That means it's involved in everything from children growing in height, to building new muscle after a workout, regenerating collagen in the skin, and even recovering from injuries.

Since tesamorelin looks almost exactly like GHRH, it can bind to the same receptors and basically have the same effect: increasing HGH levels in the blood [2]. It also increases insulin-like growth factor (IGF), another important chemical that helps regulate tissue growth [3]

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Benefits of Tesamorelin

So what are the benefits of Tesamorelin?

There are many, and researchers often see a huge difference in test subjects using tesamorelin before and after.

But it is important to be clear that the main benefit of tesamorelin is that it raises HGH levels. Several studies have confirmed that tesamorelin has this effect on its research subjects.

• One study found that tesamorelin increased HGH and IGF [4].
• Another study confirmed these results and found that tesamorelin significantly increased overnight HGH secretion [5].

Tesamorelin's main effect is that it up-regulates HGH. The other tesamorelin benefits come from that increased HGH—they're more accurately described as indirect benefits of tesamorelin.

Tesamorelin Bodybuilding

While our team was not able to find any research looking directly at the effects of tesamorelin in bodybuilding, it is believed that researchers are now intensively studying the bodybuilding effects of tesamorelin. Researchers should consult the relevant literature when designing an experiment or trial but anecdotal evidence suggests that this peptide may be dosed in the following way: 

• 1 mg of tesamorelin, daily
• 5 days a week
• Administered prior to bed

The lack of research into tesamorelin for bodybuilding indicates that further research in this area is warranted.

Tesamorelin and Lean Muscle

While there is no direct research into tesamorelin in bodybuilding, there have been studies that have found it can help build lean muscle mass in other populations. For example, one study looked at the effects of tesamorelin on building skeletal muscle in the trunk: the rectus abdominis, the obliques, the psoas major, and the paraspinal muscles [6].

After 26 weeks of a tesamorelin dosing regimen, researchers found that there was a significant increase in muscle density in all muscle groups examined, compared to a placebo [6]. They also found that there were significant increases in muscle size in several muscle groups.

These results suggest that tesamorelin can effectively enhance skeletal muscle growth.

Tesamorelin and Fat Loss

This is actually what tesamorelin has been approved by the FDA to do: get rid of visceral fat.

The majority of research on this has been done on patients with HIV that are taking anti-retroviral medications. These medications can cause a condition called lipodystrophy, which is basically the accumulation of fat around the midsection.

Tesamorelin has been shown in many studies that it is effective in increasing GH in these populations as well as in healthy populations and that it can be effective in reducing this stubborn abdominal fat [2, 7, 8, 9, 10, 11, 12].

One systematic review of the studies that look at tesamorelin for treating lipodystrophy pooled results from over 1,511 patients. The review found that tesamorelin reduced visceral adipose tissue (stomach fat) by 25.2 cm squared, on average [11].

This same review also found that tesamorelin increased lean body mass by about 1.31 kg [11].

It's not just abdominal fat that tesamorelin incinerates; it has also been found to have an effect on other fat loss and body composition measures:

• It reduces fatty deposits in the liver [11, 12]
• It significantly reduces waist circumference [2]
• It has been found to improve body image [2]

Patients with lipodystrophy will want to follow their doctor's guidelines on tesamorelin dosing. Usually, the dosage is 2 mg per day.

Researchers who wish to administer tesamorelin to test subjects can use the same dosing schedule indicated above: 

• 1 mg of tesamorelin, daily
• 5 days a week
• Administered prior to bed

Tesamorelin and Cognition

Tesamorelin isn't typically seen as a nootropic substance, but there is some research that suggests this peptide can have a significant impact on cognition.

For example, several studies have found that people with dementia perform significantly better on cognitive tasks after being administered tesamorelin compared with those in a placebo group [13, 14, 15].

In one study, older adults with mild cognitive impairments were given either tesamorelin or a placebo for 20 weeks [14]. By the end of the study, researchers found that test subjects who had received tesamorelin had changes in neurochemicals that were consistent with better brain functioning. In addition, these adults performed significantly better on a battery of cognitive tests.

But tesamorelin doesn't only benefit test subjects with cognitive impairments; research has found it can benefit healthy adults too [13, 14, 15].

Tesamorelin and Nerve Damage

Nerves are very hard to regenerate, and cases of nerve damage are permanent.

But that looks like it could change with more research into peptides. Some research has found that in some instances, tesamorelin is an effective way to repair nerve damage [16].

This is consistent with other research that shows both HGH and IGF are associated with improved nerve regeneration outcomes [17].

Tesamorelin and Cardiac Disease

Tesamorelin may also play a role in reducing the risk of developing cardiovascular disease. This is partly because it reduces fat in the midsection, which is associated with an increased risk of heart disease.

However, it also seems to reduce triglyceride levels as well as total cholesterol levels in the blood, both of which may reduce the risk of cardiovascular disease [14, 18].

Tesamorelin Side Effects

One of the tesamorelin benefits is that it raises HGH without being HGH. Supplementing HGH directly can cause very severe side effects. But because tesamorelin increases HGH indirectly using the body's own natural processes, it tends to have fewer side effects.

Still, there can be some. The most common side effects include [18]:

• redness, itching, pain, swelling, and irritation at the site of injection
• muscle aches
• diarrhea
• sweating

Despite these side effects, most research has concluded that tesamorelin is safe and well-tolerated when administered to test subjects [2, 7, 8, 9, 10, 11, 19]

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Where to Buy Tesamorelin Online? | 2023 Guide

Tesamorelin is sold as a prescription medication in many places, including the US. That means that it is possible for individuals with a prescription to buy tesamorelin from a pharmacy.

However, it is also available to researchers as a reference material, and the best place to buy it is online. The main problem facing researchers is finding a reputable vendor. We recommend Peptide Sciences and here’s why:

• They stock high-quality peptides. Peptide Sciences produces its tesamorelin in the US and tests the purity of every batch through independent laboratory analysis. They then post the results on their site for researchers to view. This lets researchers confirm the purity of what they are buying before placing an order.
• They offer convenient, fast shipping. Peptide Sciences ships peptides worldwide. Shipments within the US typically take between 2 and 3 days while international orders take 10 days or less.
• They accept a range of convenient, secure payment options. Researchers want to choose a legitimate vendor that won't steal or sell personal information or data. Peptide Sciences has a secure payment system and accepts a wide range of payment options including debit and credit cards and cryptocurrencies like Bitcoin and Ethereum.
• They offer great customer service. We've always been impressed at how accessible the customer support team is and how great they are at solving problems. They have a great guarantee that ensures that if the wrong product is shipped, or there are delays, customers will receive a free reshipment or full refund. 

Overall, there’s no doubt in our minds that Peptide Sciences is the premier tesamorelin vendor currently serving researchers.

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Bacteriostatic Water for Injection

To comply with the proper methods of peptide handling, you must have the right materials. Particularly when preparing Tesamorelin, as well as injecting and storing it, you will need items such as bacteriostatic water, sterile needles, insulin syringes, and more.

The quest for all of these materials can put a damper on your peptide research. But, it doesn’t have to!

We at Peptides.org have found a single quality provider of research materials to easily solve your supply challenges.

BacteriostaticWater.org

This site tops our list with an impressive selection of supply kits, replete with all the materials needed in peptide research. Choose between two offerings from BacteriostaticWater.org to conveniently receive the full range of essentials.

Select the starter research kit to enjoy:

• Bacteriostatic Water (30mL) – 3x
• Insulin Syringes (0.5 cc/mL x 29g x ½) – 100x
• Alcohol Prep Pads – 200x
• Sterile Empty Glass Vial (10mL) – 1x
• Large Needles + Syringes Combo (3cc x 21g x 1) – 10x

More experienced handlers may prefer the premium research kit, stocked with:

• Bacteriostatic Water (30mL) – 5x
• Insulin Syringes (0.5 cc/mL x 29g x ½) – 200x
• Alcohol Prep Pads – 200x
• Sterile Empty Glass Vial (10mL) – 2x
• Large Needles + Syringes Combo (3cc x 21g x 1) – 20x

You are guaranteed to appreciate the benefits of a deluxe research kit from our most esteemed supplier.

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Tesamorelin Benefits | Verdict

So what are the benefits of Tesamorelin?

Tesamorelin has a proven ability to promote lean muscle gains and reduce body fat, especially around the midsection. Other benefits may include repairing damaged nerve tissue, reducing the risk of cardiovascular diseases, and even improving cognition.

Given the long list of potential tesamorelin benefits, it's little wonder that so many in the research community are interested in testing out its effects even further. We strongly suggest Peptides Sciences as a safe and reliable vendor.

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