Titus Thorne

Last Updated November 17, 2021

Titus Thorne

 November 17, 2021

Want to know how much tesamorelin costs?

Many researchers are curious about the cost of this growth hormone peptide when designing and conducting experiments, and many patients with lipodystrophy want to know where they can get this drug at the best prices.

That’s why we created this A-Z guide about the cost of tesamorelin (Egrifta). Below, we’ll explain exactly what tesamorelin is, how much it costs and where to order it online for the best prices.

Our aim for this guide is to help you order from a legitimate supplier and avoid paying more than you should. Let’s dive in!

Buy Tesamorelin from the #1 online Peptides vendor in the world: Peptides Sciences

Disclaimer: ResearchPeptides.org contains information about products that are intended for laboratory and research use only, unless otherwise explicitly stated. This information, including any referenced scientific or clinical research, is made available for educational purposes only. ResearchPeptides.org makes every effort to ensure that any information it shares complies with national and international standards for clinical trial information and is committed to the timely disclosure of the design and results of all interventional clinical studies for innovative treatments publicly available or that may be made available. However, research is not considered conclusive. ResearchPeptides.org makes no claims that any products referenced can cure, treat or prevent any conditions, including any conditions referenced on its website or in print materials.


What is Tesamorelin?

Tesamorelin (also known as “tesamorelin acetate”) is a stabilized synthetic peptide analogue of growth hormone-releasing hormone (GHRH) that was developed by the Candian company Theratechnologies [1]. It’s commonly sold under the trade name “Egrifta” and is primarily used to simulate the production and release of growth hormone (GH) in HIV-infected patients.

In 2010, Egrifta was approved by the United States Food & Drug Administration (FDA) to treat patients with lipodystrophy (excess abdominal fat) caused by long-term antiretroviral therapy. As a peptide, Egrifta contains short chains of amino acids, the building blocks of proteins [2]. It’s also a hormone, which means that it has an effect on the human endocrine system and sends chemical signals that help to regulate the level of GH in the body.

Human growth hormone

Tesamorelin is chemically identical to GHRH, which is made naturally in the body. This hormone's job is to work as part of the system that regulates the amount of human growth hormone (HGH) that gets produced and secreted. HGH is essential for the body to grow and repair itself. It plays a role in all kinds of cellular synthesis and repair functions. While HGH is particularly important to children as they're growing, it's also important for adults: The level of HGH in the body naturally declines with age.

While Egrifta’s only approved use in the United States is to treat Lipodystrophy in patients with HIV, anecdotal evidence suggests that healthy individuals including athletes and bodybuilders use this peptide to improve their appearance, increase their athletic performance and recover from injury. The World Anti-Doping Agency (WADA) has banned the use of all growth hormone-releasing hormones (GHRHs) including tesamorelin in sports, which strongly suggests that they help enhance athletic performance [3].

Tesamorelin increases HGH

Fortunately, it's possible to increase HGH levels indirectly by administering peptides that up-regulate the production of HGH. These can be just as effective as taking HGH directly and can have many fewer adverse effects.

Tesamorelin is one such HGH secretagogue. Because it’s chemically similar to GHRH and binds to the same receptors as GHRH, it has the same effect as higher HGH levels in the blood [4].


tesamorelin


Benefits of Tesamorelin

Tesamorelin has been widely researched and is an FDA-approved drug that’s used to treat HIV patients with lipodystrophy. Its research-backed benefits include:

  • Increased muscle area and decreased muscle fat in HIV-infected adults [5].
  • Decreased abdominal fat in patients with HIV-related lipodystrophy [6].
  • Ability to trigger lipolysis (fat burning) in patients with lipohypertrophy, especially visceral adipose tissue (VAT) around the midsection [7].
  • Ability to increase levels of NAAG (N-acetylaspartylglutamate) and GABA (Gamma aminobutyric acid), and decrease levels of MI (myo-inositol), an osmolyte linked to Alzheimer disease, after 20 weeks in adults with mild cognitive impairment [8].

It should be noted that tesamorelin’s only approved use is to treat HIV patients and to date there have been no scientific studies on the effects of tesamorelin supplementation in otherwise healthy individuals with regards to increased muscle or decreased fat.


Tesamorelin Side Effects

Tesamorelin has been well researched and is generally considered to be well-tolerated by most HIV patients. However, studies have indicated that some patients, typically fewer than five percent, may experience side effects. The most common ones include irritation around the injection site, increased sweating, muscle aches and diarrhea [5].

According to a registry analysis of safety data from growth hormone manufacturers' registries published between 1988 and 2016, there is no evidence of an increased risk of mortality, stroke, leukaemia, type 2 diabetes, or new malignancy in healthy adult patients treated with GH [9]. The only patients with an increased risk of developing one of these conditions were those with pre-existing risk factors. The study’s authors concluded that patients with risk factors for these conditions “should be treated with caution” and closely “monitored during follow-up.”

Despite strong anecdotal evidence that GH is widely used by athletes and bodybuilders, little is known about the long-term side effects of GH supplementation in healthy individuals. In a recent systematic review of available data about renal (kidney) safety of GH and steroids, researchers found that “GH's exact effect on the kidney at doses used by athletes and bodybuilders has not yet been clarified.” This indicates that long-term clinical studies into the effects of GH on the liver may be warranted [10].


How Much Does Tesamorelin Cost?

So how much does tesamorelin cost?

Well, it depends on who you are and where you buy it.

Tesamorelin for sale at pharmacies

Tesamorelin is FDA-approved as a prescription medication to reduce excess abdominal fat in HIV patients that have received long-term antiretroviral therapy. Because it's a prescription medication, patients can buy it from a pharmacy. But, it costs significantly more.

At the time of writing, Costco sells Egrifta subcutaneous powder at the lowest price and charges $5,901.04 for 30 vials of 2 mg of tesamorelin [11]. This works out at $196 per vial, or $98 per dose. Keep in mind, that's after using a coupon. Without the coupon, the cost is $8,134 for 30 vials of 2 mg. That's $271 per vial, or $135 per dose.

That's very expensive.

Tesamorelin for sale online

Tesamorelin costs much less for researchers seeking to acquire the peptide for their tests or experiments.

Peptide Sciences currently lists 10 vials of 5 mg of tesamorelin — about 50 doses — for sale at $625. That's just $12.50 per dose.

That’s an 87 percent differential for researchers who buy tesamorelin online compared to patients who buy it at the pharmacy.

Administering one tesamorelin cycle of 5 days a week for 2 months would save you roughly $3,400.

If you’re looking to buy tesamorelin for research purposes, purchasing online is the best (and only) way to go.


Tesamorelin Dosage

Roughly 10 to 40 percent of HIV patients receiving long-term antiretroviral therapy (ART) will develop a metabolic condition known as lipodystrophy, which is characterized by an accumulation of fat on the midsection and insulin resistance [12]. Patients with this condition will be directed by their doctor to dose tesamorelin in the following way:

  • One subcutaneous injection, daily
  • Each injection containing a dosage of 2 mg
  • Five days a week
  • At least 90 minutes after eating
  • At night, before bed

While there is no scientific evidence that growth hormone supplementation improves athletic performance, anecdotal evidence suggests that this practice is becoming more widespread among athletes and bodybuilders [13]. Anecdotal reports indicate that tesamorelin is dosed in the following way:

  • One subcutaneous injection, daily
  • Each injection containing a dosage of 1 mg
  • Five days a week
  • At least 90 minutes after eating
  • At night, before bed

Studies have shown that Egrifta (tesamorelin) does not interact adversely with food, has no effect on glycemic control or insulin response [14] and does not aggravate glucose levels [15].


Tesamorelin & CJC-1295?

From a research standpoint, tesamorelin and CJC-1295 make for an interesting comparison. The similarities between these two peptides include:

  • Both are growth hormone-releasing hormones (GHRH) analogues;
  • Both are administered by subcutaneous injection;
  • Both can enhance GH secretion for prolonged periods;
  • Both are prohibited in sports according to the regulations of the World Anti-Doping Agency (WADA).

The main difference between these two peptides is that while tesamorelin’s research has been restricted solely to HIV-infected adult patients, CJC-1295 has been tested on healthy adults. The results of two randomized, placebo-controlled, double-blind, ascending dose trials found that CJC-1295 “increases GH and IGF-I levels in healthy adults” and is “safe and relatively well tolerated” [16].

In terms of administering these two peptides simultaneously, scientific data is lacking. While there are anecdotal reports of athletes and bodybuilders injecting biosynthetic forms of growth hormone (such as tesamorelin and CJC-1295) in the belief that these peptides will increase their endogenous GH secretion, there is no valid evidence for the efficacy of this practice [13].


Do You Need a Prescription to Buy Tesamorelin Online?

No, tesamorelin is 100% legal to buy — provided you’re using it to conduct research.

Individuals requiring tesamorelin as a prescription medication for their lipodystrophy do need a prescription.

But, you don't need a prescription to buy tesamorelin online for research purposes. Scientists and researchers can buy tesamorelin completely legally by simply finding an online vendor.


tesamorelin


Where to Buy Tesamorelin Online? | 2021 Guide

There are many online vendors that sell research peptides — you've got plenty of choice.

But a word of caution: Make sure to do your research to determine whether the vendor you've chosen is legitimate or not. There are lots of vendors that aren't, and they may sell you a product that has fillers in it. That means your tesamorelin might not work, or worse, it could be dangerous.

Make sure that you look for a vendor that has:

  • A track record of providing high-quality products. Look for good reviews from third-party, independent websites.
  • Proof of product quality. A good company will publish the results from chemical analyses so you can see that it's pure.
  • Secure payment. You want to make sure your information is encrypted. Ideally, you'll have a broad choice of payment options, too.
  • A guarantee. What happens if you don't receive your product or it's not what you ordered? You want to make sure there is a reasonable process in place so that you can get the problem fixed.
  • Customer service. Solid customer service that will reply promptly to your questions and comments is also key.

The #1 Place to Legally Order Tesamorelin Online

We only trust one vendor with our peptide orders, and that’s Peptide Sciences.

The reason is that we've tried many different vendors and only Peptide Sciences has consistently been able to deliver. They offer solid peptides at very reasonable prices.

Here's what we love about Peptide Sciences:

Fast, secure, global shipping

Peptide Sciences is based in the United States, and if you’re also located in the US, you'll usually get your shipment within 2-3 days. It usually takes a bit longer for customers outside of the US — up to 10 days — but that's still really fast compared to other suppliers.

Best of all, this vendor charges a $15 flat fee for shipping, but if you buy more than $200, it's free.

The discounts are great

You can buy individual vials or you can buy in bulk and get a discount. For example, if you buy 5 vials of tesamorelin, you'll save 5%. If you buy 10 vials, you'll save 9%. These discounts add up.

You also get a gift of 30 ml of bacteriostatic water if you spend over $300.

Convenient, secure payment

Peptide Sciences offers many payment options, including:

  • Most major credit cards
  • Cyber currencies like Bitcoin, Ethereum, and Litecoin
  • Other e-payment options like Apple Pay and Venmo
  • Electronic check

Fantastic customer service

Honestly, this is where Peptide Sciences really shines. Every time we've tried to get in touch by phone or email, we've been impressed by how easy it is to get help. They've always solved any problem we've had quickly and professionally.

The best quality around

You need the highest quality peptides for your research.

Peptide Sciences guarantees a super high-quality product — exceeding 99% purity. They also get an independent laboratory to test their product and then post a certificate of that analysis right on their website for you to confirm.

These are the peptides that are used in clinical research and human trials, so you can be sure it's exactly what you need.

Buy Tesamorelin from our #1 recommended vendor...


tesamorelin


Tesamorelin Costs | Verdict

How much does tesamorelin cost? It depends, but you can find it for around $12.50 per dose when you shop with our recommended vendor.

Overall, tesamorelin is widely available to researchers at reasonable prices and there is a good selection of vendors to source this research peptide from.

Researchers interested in conducting studies with tesamorelin can pay significantly less by ordering in bulk. Low prices coupled with free international shipping make tesamorelin highly attractive to researchers interested in investigating this peptide's benefits and long-term side effects.


References

  1. Patel, A., Gandhi, H., & Upaganlawar, A. (2011). Tesamorelin: A hope for ART-induced lipodystrophy. Journal of Pharmacy And Bioallied Sciences, 3(2), 319.
  2. Food and Drug Administration (2020). Impact Story: Developing the Tools to Evaluate Complex Drug Products: Peptides. Retrieved March 28, 2020. Fda.gov
  3. Knoop A, Thomas A, Fichant E, Delahaut P, Schänzer W, Thevis M. Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS. Anal Bioanal Chem. 2016 May;408(12):3145-53. doi: 10.1007/s00216-016-9377-3. Epub 2016 Feb 15. PMID: 26879649; PMCID: PMC4830873.
  4. Food and Drug Administration (2010). Chemistry Reviews: Application 22-505. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2010/022505Orig1s0
    00ChemR.pdf
  5. Adrian, S., Scherzinger, A., Sanyal, A. et al. The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV. J Frailty Aging 8, 154–159 (2019). https://doi.org/10.14283/jfa.2018.45
  6. Dhillon, S. Tesamorelin. Drugs 71, 1071–1091 (2011). https://doi.org/10.2165/11202240-000000000-00000
  7. Clinical Review Report: Tesamorelin (Egrifta) [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Aug. Executive Summary. Available from: https://www.ncbi.nlm.nih.gov/books/NBK539124/
  8. Friedman SD, Baker LD, Borson S, et al. Growth Hormone–Releasing Hormone Effects on Brain γ-Aminobutyric Acid Levels in Mild Cognitive Impairment and Healthy Aging. JAMA Neurol. 2013;70(7):883–890. doi:10.1001/jamaneurol.2013.1425
  9. Stochholm K, Kiess W. Long-term safety of growth hormone-A combined registry analysis. Clin Endocrinol (Oxf). 2018 Apr;88(4):515-528. doi: 10.1111/cen.13502. Epub 2017 Nov 20. PMID: 29055168.
  10. Davani-Davari D, Karimzadeh I, Khalili H. The potential effects of anabolic-androgenic steroids and growth hormone as commonly used sport supplements on the kidney: a systematic review. BMC Nephrol. 2019 May 31;20(1):198. doi: 10.1186/s12882-019-1384-0. PMID: 31151420; PMCID: PMC6545019.
  11. oodRx.com (n.d.). Egrifta. https://www.goodrx.com/egrifta-sv
  12. Garg A. Acquired and inherited lipodystrophies. N Engl J Med. 2004 Mar 18;350(12):1220-34. doi: 10.1056/NEJMra025261. PMID: 15028826.
  13. Macintyre JG. Growth hormone and athletes. Sports Med. 1987 Mar-Apr;4(2):129-42. doi: 10.2165/00007256-198704020-00004. PMID: 3299611.
  14. Clemmons DR, Miller S, Mamputu JC. Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial. PLoS One. 2017 Jun 15;12(6):e0179538. doi: 10.1371/journal.pone.0179538. PMID: 28617838; PMCID: PMC5472315.
  15. Falutz J, Allas S, Mamputu JC, Potvin D, Kotler D, Somero M, Berger D, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S. Long-term safety and effects of tesamorelin, a growth hormone-releasing factor analogue, in HIV patients with abdominal fat accumulation. AIDS. 2008 Sep 12;22(14):1719-28. doi: 10.1097/QAD.0b013e32830a5058. PMID: 18690162.
  16. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805. doi: 10.1210/jc.2005-1536. Epub 2005 Dec 13. PMID: 16352683.

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