Titus Thorne

Last Updated May 11, 2022

Titus Thorne

 May 11, 2022

Researchers aware of the potential benefits of ipamorelin may be curious about how much ipamorelin costs. Numerous studies have shown that ipamorelin can stimulate both growth hormone (GH) and insulin-like growth factor 1 (IGF-1) in animals, yet there’s still a paucity of data on its effects in humans. This has led many researchers to view ipamorelin as an ideal candidate for further investigation.

Researchers interested in studying ipamorelin’s efficacy for treating male hypogonadism or its safety and long-term side effects will need to know where to acquire this peptide at reasonable prices.

This guide will provide a summary of everything that researchers need to know about the costs involved when researching ipamorelin. Researchers will learn where to order research-grade ipamorelin online for the best prices.

Want to discover our No. 1 recommendation for the best ipamorelin vendor? Keep reading to the end of this guide to find out!

Buy Ipamorelin from the #1 online Peptides vendor in the world...

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What is Ipamorelin?

Ipamorelin is a type of research peptide known as a “pentapeptide” meaning that it contains five amino acids. Its main function is that it mimics ghrelin [1], a naturally occurring hormone found mostly in the gastrointestinal (GI) tract that influences several key anabolic processes in the body. These include [2]:

  • Fat processing
  • Appetite suppression
  • Overall energy usage

Ipamorelin’s ability to mimic ghrelin means that it’s often referred to as a “ghrelin mimetic”; however, it’s more commonly referred to as a growth hormone (GH) secretagogue, or GHS. This is because it binds to the same receptors as ghrelin (known as GHSR-1a receptors) and increases the amount of GH and IGF-1 that’s secreted while reducing the amount of somatostatin, a GH-inhibiting hormone [3].


ipamorelin


Benefits of Ipamorelin

Animal and human studies have shown that ipamorelin acts as a potent GH and IGF-1 stimulator and offers numerous potential benefits. Here’s a brief overview of the available research.

Potential treatment for male hypogonadism

While testosterone remains the gold standard treatment for hypogonadism management, ipamorelin’s ability to stimulate overall weight gain has led to it being identified as a potential novel adjunctive therapy for male hypogonadism. It can increase endogenous GH and IGF-1 to levels similar to those observed with exogenous GH therapy without exceeding physiologic norms [4].

Potential post-op treatment for open laparotomy

Research has shown that ipamorelin can accelerate gastric emptying in animals [5]. Its efficacy for reducing the amount of time to the first tolerated meal for patients who had undergone either open or laparoscopic bowel resection has been investigated in one phase II clinical trial [6]. While the trial found that ipamorelin was no better than a placebo for this purpose [4], the findings suggested that it may improve recovery times for open laparotomy patients [7].

Purported anabolic and fat loss benefits

Despite strong research interest in the application of ipamorelin to improve athletic performance, body composition, and appearance, there is no published research showing that ipamorelin offers these benefits in humans. 

Animal studies involving both GH-deficient and non-GH-deficient mice have shown that twice-daily ipamorelin injections lead to significant increases in body weight (15.3% and 16.9% respectively) [8] and stimulate GH secretion, which is lipolytic [9]. 

Research involving recreational athletes has linked growth hormone use (not ipamorelin, specifically) to increased muscle mass, decreased fat mass, and improved sprint ability [10], but it is not known whether ipamorelin offers similar benefits. 

Purported anti-aging benefits

Many researchers are interested in ipamorelin’s purported anti-aging benefits despite a distinct lack of supporting research. For instance, one study found that growth hormone (GH) secretagogues similar to ipamorelin helped increase lean body mass and decrease fat mass in a group of seniors [11], but it is not known whether ipamorelin offers these benefits. 

Given that long-term research has linked elevated GH levels with lower life expectancy (by accelerating the aging process) [12], further research is required to determine whether ipamorelin offers anti-aging benefits. 

While this review of the ipamorelin research clearly highlights the lack of data supporting many of the key claims made about ipamorelin’s potential and purported benefits, it does open numerous opportunities for further investigation.


Ipamorelin Side Effects?

Ipamorelin’s safety and efficacy have yet to be evaluated in long-term human clinical trials so little is known about its potential side effects. To date, ipamorelin has been involved in just one such trial: a small, proof-of-concept study that involved just 114 participants and lasted a mere seven days [6]. As of writing, ipamorelin remains a non-FDA-approved research peptide.

Based on what little data exists, ipamorelin does not appear to cause adverse effects when taken on a short-term basis and the few reported side effects seem similar to those caused by other GHSs like sermorelin [6]. These include:

  • Transient fever
  • Redness, itching, and rashes
  • Dry mouth
  • Sensitivity at the site of injection
  • Nausea
  • Headaches

However, based on the findings of long-term research involving exogenous GH therapy (not ipamorelin, specifically) we can see that elevated GH levels have been linked to severe side effects, including:

  • Scoliosis
  • Hypertension [13]
  • Insulin resistance [13]

Researchers interested in running clinical trials with ipamorelin would be well-advised to exclude test subjects’ pre-existing conditions such as hypertension or diabetes.

Following this brief overview of ipamorelin’s benefits and side effects, let’s turn our attention to the question at hand: how much does ipamorelin cost?


How Much Does Ipamorelin Cost?

Researchers familiar with the benefits and side effects of ipamorelin may be curious about how much this research peptide costs.

The price of ipamorelin varies depending on three main factors:

  • Where the peptide is sourced from
  • The specific product or blend
  • The quantity of peptide ordered

We never go cheap when talking about research peptides, and that’s one of the many reasons we exclusively recommend Peptide Sciences. They offer research-grade ipamorelin at the best prices.

They sell two main ipamorelin products:

They also sell the following ipamorelin blends:

Now let’s look at the prices.

  • A single vial of Ipamorelin 2mg costs $26.50, but researchers can save 6% when they order 5 vials and 8% on orders of 10 vials or more.
  • A single vial of Ipamorelin 5mg costs $46.00, but researchers can save 5% when they order 5 vials and 9% on orders of 10 vials or more.
  • Researchers interested in ordering a blend of ipamorelin and another peptide will note that individual vials range in price from $78-80. Researchers can save 4-8% on orders of five or more, and 10-11% on orders of ten or more.

Ordering ipamorelin online offers more flexibility in terms of both lower cost and more choices for dosages.


Ipamorelin Dosage vs. Costs

In the absence of alternative data, researchers can consult the findings of a 2014 study by Beck et al into the use of ipamorelin for the management of postoperative ileus in bowel resection patients as a guide of how best to dose this research peptide in human subjects.

Participants in the study received twice-daily 0.03-mg/kg ipamorelin doses via intravenous infusion on postoperative days 1 to 7.

These findings indicate that ordering larger ipamorelin 5mg vials in bulk (more than 10) would be the most economical way for researchers to pay for ipamorelin during a long-term study.

Researchers can click here for the best ipamorelin prices!


Do Researchers Need a Prescription to Buy Ipamorelin Online?

It is not necessary for researchers to have a prescription to purchase ipamorelin online since it is available as a reference material for qualified researchers.

Here’s what researchers will see when they order ipamorelin on the Peptides Sciences website:

buy ipamorelin

Pretty straightforward!

Non-researchers interested in ipamorelin should contact a doctor or healthcare professional that specializes in peptides for consultation.


Ipamorelin & CJC-1295?

Peptide Sciences offer three different blends that contain both ipamorelin and CJC 1295. CJC-1295 is a peptide that is a synthetic analogue of growth hormone-releasing hormone (GHRH) and is a potent stimulator of both GH and IGF-1.

Research indicates that using CJC 1295 in combination with ipamorelin in a blend can stimulate the GH axis to a greater extent than using each peptide individually. Each peptide utilizes different receptors in the body and this has the effect of amplifying the release of GH while simultaneously boosting GH concentration levels. Combining these two peptides and stimulating the GH axis through two different pathways is believed to increase the benefits.

While neither ipamorelin nor CJC-1295 have passed human clinical trials and neither has received FDA approval, they are both popular with researchers who want to study their efficacy for treating symptoms of hypogonadism and other related conditions.


ipamorelin


Ipamorelin Costs | Verdict

Our overview of the available research clearly shows current data on ipamorelin’s safety and efficacy remains lacking. While this opens up numerous opportunities for further research, researchers are bound to want to know how much ipamorelin costs before deciding whether to run studies.

As stated above, the easiest and safest way for researchers to obtain ipamorelin is to place an order online. Researchers should take care to use legitimate vendors by following our guidelines, as well as by comparing the costs for the dosages required in the experiment or trial. 

We always recommend Peptide Science as the best place to order ipamorelin online because we’ve had amazing experiences using it and we know they’re a legitimate place for researchers to get research-grade peptides for test subjects. They offer fairly priced ipamorelin, have secure transactions, independent reviews, and a solid refund policy. And, they publish the lab test results of their products so that researchers can have confidence in the quality of their product before they place an order.

Researchers are highly advised to contact our recommended vendor Peptide Sciences before placing an order for ipamorelin.

Buy ipamorelin from our #1 recommended vendor…

Buy Ipamorelin from our #1 recommended vendor...


References

  1. Kojima M, Kangawa K. Ghrelin: structure and function. Physiol Rev. 2005 Apr;85(2):495-522. doi: 10.1152/physrev.00012.2004. PMID: 15788704.
  2. Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR. Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab. 2001 Dec;86(12):5992. doi: 10.1210/jcem.86.12.8111. PMID: 11739476.
  3. Raun, K, Hansen, B., Johansen, N., Thogersen, H, Madsen, K, Ankersen, M, & Andersen, P. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology. 139 (5): 552–561.
  4. Sinha, Deepankar K et al. “Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.” Translational andrology and urology vol. 9,Suppl 2 (2020): S149-S159. doi:10.21037/tau.2019.11.30
  5. Greenwood-Van Meerveld B, Tyler K, Mohammadi E, Pietra C. Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus. J Exp Pharmacol. 2012 Oct 19;4:149-55. doi: 10.2147/JEP.S35396. PMID: 27186127; PMCID: PMC4863553.
  6. Beck DE, Sweeney WB, McCarter MD; Ipamorelin 201 Study Group. Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Int J Colorectal Dis. 2014 Dec;29(12):1527-34. doi:10.1007/s00384-014-2030-8. Epub 2014 Oct 21. PMID: 25331030.
  7. Delaney CP, Marcello PW, Sonoda T, Wise P, Bauer J, Techner L. Gastrointestinal recovery after laparoscopic colectomy: results of a prospective, observational, multicenter study. Surg Endosc. 2010 Mar;24(3):653-61. doi: 10.1007/s00464-009-0652-7. Epub 2009 Aug 18. PMID: 19688390.
  8. Estrada, R. Cañete; Jiménez-Reina, L.; de la Torre, M.J.; Bernal, J. (2002). “Chronic In Vivo Ipamorelin Treatment Stimulates Body Weight Gain and Growth Hormone (GH) Release In Vitro in Young Female Rats. European Journal of Anatomy. 6(1): 37–46.
  9. Lall S, Tung LY, Ohlsson C, Jansson JO, Dickson SL. Growth hormone (GH)-independent stimulation of adiposity by GH secretagogues. Biochem Biophys Res Commun. 2001 Jan 12;280(1):132-8. doi: 10.1006/bbrc.2000.4065. PMID: 11162489.
  10. Meinhardt U, Nelson AE, Hansen JL, Birzniece V, Clifford D, Leung KC, Graham K, Ho KK. The effects of growth hormone on body composition and physical performance in recreational athletes: a randomized trial. Ann Intern Med. 2010 May 4;152(9):568-77. doi: 10.7326/0003-4819-152-9-201005040-00007. PMID: 20439575.
  11. George R. Merriam, Suzanne Barsness, David Buchner, Monica Kletke, Lawrence H. Larsen, Karen E. Moe, Robert S. Schwartz, and Michael V. Vitiello.Journal of Anti-Aging Medicine.Dec 2001.331-343.http://doi.org/10.1089/10945450152850650
  12. Bartke A. Growth Hormone and Aging: Updated Review. World J Mens Health. 2019 Jan;37(1):19-30. doi: 10.5534/wjmh.180018. Epub 2018 May 11. PMID: 29756419; PMCID: PMC6305861.
  13. Honeyman, T. W., Goodman, M. H., & Fray, J. C. (1983). The effects of growth hormone on blood pressure and renin secretion in hypophysectomized rats. Endocrinology, 112(5), 1613-1617.

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